Description

1-Bromo-4-Methoxy-2-Methyl-5-Nitrobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research and development chemists, process development scientists, and manufacturers in fine chemical production for creating active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those with complex aromatic or heterocyclic structures.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the bromo and nitro groups offer sites for further functionalization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate in the production of complex azo dyes and other high-performance colorants.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination.
• Academic and Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	1-Bromo-4-Methoxy-2-Methyl-5-Nitrobenzene
CAS No.	89978-56-3
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	4-Bromo-5-Methoxy-2-Methyl-1-Nitrobenzene; 2-Methyl-4-Bromo-5-Methoxynitrobenzene; 5-Methoxy-2-Methyl-4-Bromonitrobenzene; 1-Bromo-4-Methoxy-2-Methyl-5-Nitro-Benzene; 89978-56-3; 4-Bromo-5-methoxy-2-methylnitrobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Methoxy-2-Methyl-5-Nitrobenzene is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.