Description

4-Methoxy-8-Nitroquinoline is a specialized quinoline derivative characterized by its methoxy and nitro substituents, which impart unique chemical reactivity and photophysical properties. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those with quinoline-based pharmacophores for antimicrobial or anticancer activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Serves as a starting material for creating more complex nitrogen-containing heterocycles through further functionalization reactions.
• Material Science: Investigated for its potential application in the creation of organic electronic materials, dyes, and photoactive compounds.
• Chemical Research: Employed in academic and industrial R&D for studying nitration and substitution reactions on quinoline systems.
• Coordination Chemistry: Potential ligand for metal complexes due to the nitrogen donor atom in the quinoline ring.

Basic Information

Product Name	4-Methoxy-8-Nitroquinoline
CAS No.	89770-28-5
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	8-Nitro-4-methoxyquinoline; 4-Methoxy-8-nitro-quinoline; Quinoline, 4-methoxy-8-nitro-; 4-Methoxyquinolin-8-yl nitrate (incorrect but common alias); 8-Nitro-4-quinolinol methyl ether
EINECS	Contact for details

Quality Control

Our 4-Methoxy-8-Nitroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and physical characterization. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.