Description

3-((Benzyloxycarbonylamino)Methyl) Benzoic Acid is a key protected amino acid derivative, serving as a versatile and high-purity building block in advanced organic synthesis. Its primary value lies in providing a stable, orthogonal protecting group for amines, enabling precise and complex multi-step reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of peptide-based therapeutics, active pharmaceutical ingredients (APIs), and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis.
• Organic Synthesis Building Block: Facilitates the construction of complex molecular architectures in medicinal chemistry and material science research.
• Protecting Group Reagent: The benzyloxycarbonyl (Cbz) group provides orthogonal protection for amines during multi-step synthetic sequences.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Chemical Biology Research: A valuable tool for probing biological systems and developing enzyme inhibitors or modulators.

Basic Information

Product Name	3-((Benzyloxycarbonylamino)Methyl) Benzoic Acid
CAS No.	89760-77-0
Molecular Formula	C16H15NO4
Molecular Weight	285.29 g/mol
Synonyms	3-[(Cbz-amino)methyl]benzoic acid; 3-[(Benzyloxycarbonylamino)methyl]benzoic acid; 3-(Cbz-aminomethyl)benzoic acid; Benzoic acid, 3-[[[(phenylmethoxy)carbonyl]amino]methyl]-; 3-(N-Cbz-aminomethyl)benzoic acid; 3-(CbzNHCH2)C6H4CO2H; Z-AMB-OH; Cbz-AMB-OH
EINECS	Contact for details

Quality Control

Our 3-((Benzyloxycarbonylamino)Methyl) Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliable supply and traceability for critical development and production workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.