Description

4-Chloro-7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block prized for its unique structural motifs. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its quinoline core and halogen/trifluoromethyl substituents enable precise molecular design. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the bioactivity of the quinoline scaffold.
• Material Science Research: Serves as a building block for developing organic electronic materials, ligands for catalysis, and fluorescent probes.
• Chemical Biology & Proteomics: Employed in the design of molecular tools, enzyme inhibitors, and activity-based probes for biological target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up development.

Basic Information

Product Name	4-Chloro-7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid
CAS No.	89524-63-0
Molecular Formula	C11H5ClF3NO2
Molecular Weight	275.61 g/mol
Synonyms	4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 4-chloro-7-(trifluoromethyl)-; 4-Chloro-7-trifluoromethylquinoline-3-carboxylic acid; 89524-63-0; 4-Chloro-7-(trifluoromethyl)-3-quinolinecarboxylic acid; 4-Chloro-7-trifluoromethyl-3-quinolinecarboxylic acid; Quinoline-3-carboxylic acid, 4-chloro-7-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-7-(Trifluoromethyl)Quinoline-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates, ensuring the material is suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.