Description

4-Bromo-7-Methoxy-2(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound matters for its critical role in facilitating complex molecular transformations, particularly in the synthesis of advanced pharmaceutical intermediates and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific functional groups for activity optimization.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis, leveraging the quinoline core for metal coordination.
• Fluorescent Probe Synthesis: Utilized to construct quinoline-based fluorescent dyes and sensors for biological imaging and diagnostic applications.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.

Basic Information

Product Name	4-Bromo-7-Methoxy-2(Trifluoromethyl)Quinoline
CAS No.	89446-63-9
Molecular Formula	C₁₁H₇BrF₃NO
Molecular Weight	306.08 g/mol
Synonyms	4-Bromo-7-methoxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-bromo-7-methoxyquinoline; 7-Methoxy-4-bromo-2-trifluoromethylquinoline; Quinoline, 4-bromo-7-methoxy-2-(trifluoromethyl)-; 89446-63-9; 4-Bromo-7-methoxy-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-7-Methoxy-2(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports compliance with cGMP and ISO standards for reliable integration into your critical R&D and production workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.