Description

7-Bromo-2-Chloro-4-Methyl-1-Azanaphthalene is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring bromine and chlorine substituents on a naphthyridine core, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where its halogenated structure can contribute to biological activity and stability.
• Material Science: Serves as a building block for creating organic semiconductors, liquid crystals, and photoactive materials due to its rigid, conjugated framework.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex functionalities into target molecules.
• Academic & Contract Research: Essential for fundamental research in heterocyclic chemistry and for contract research organizations (CROs) providing custom synthesis services.

Basic Information

Product Name	7-Bromo-2-Chloro-4-Methyl-1-Azanaphthalene
CAS No.	89446-52-6
Molecular Formula	C10H6BrClN
Molecular Weight	256.52 g/mol
Synonyms	7-Bromo-2-chloro-4-methyl-1,8-naphthyridine; 2-Chloro-7-bromo-4-methyl-1,8-naphthyridine; 1,8-Naphthyridine, 7-bromo-2-chloro-4-methyl-; 4-Methyl-7-bromo-2-chloro-1,8-naphthyridine; 7-Bromo-2-chloro-4-methyl-[1,8]naphthyridine; 89446-52-6; 7-Br-2-Cl-4-Me-1,8-Naphthyridine
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-Chloro-4-Methyl-1-Azanaphthalene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality assurance supports your research and development needs with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.