Description

Potassium Bis(Boc)Amide is a versatile and highly reactive organometallic reagent, primarily used as a powerful base for the generation of hindered amide anions. Its core value proposition lies in its ability to facilitate challenging deprotonation reactions under mild conditions, which is critical for synthesizing complex, high-value molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient synthetic methodologies. The product is supplied under the identifier CAS NO 89004-82-0.

Application

• As a strong, non-nucleophilic base for the deprotonation of weakly acidic N-H protons in amides, sulfonamides, and related compounds.
• Key reagent in peptide mimetic and heterocycle synthesis, enabling the formation of sensitive intermediates.
• Facilitates asymmetric synthesis and the preparation of sterically hindered enolates for carbon-carbon bond formation.
• Used in pharmaceutical process chemistry for the scalable production of active pharmaceutical ingredients (APIs) and key intermediates.
• Employed in polymer chemistry for initiating anionic polymerizations or modifying polymer chains.
• Valuable in academic and industrial R&D for exploring new reaction pathways and synthesizing novel organic compounds.

Basic Information

Item	Detail
Product Name	Potassium Bis(Boc)Amide
CAS No.	89004-82-0
Molecular Formula	C10H18KNO4
Molecular Weight	255.35 g/mol
Synonyms	Potassium tert-Butoxycarbonylimide; Potassium Di-tert-butoxycarbonyl Amide; Potassium N,N-Bis(tert-butoxycarbonyl)amide; Potassium N,N-Di-Boc Amide; Potassium Hexamethyldisilazane Analog (Boc-protected); KBTA; Potassium Bis(Boc)azanide
EINECS	Contact for details

Quality Control

Our Potassium Bis(Boc)Amide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes comprehensive analytical testing, including assay by titration and impurity profiling, to meet the stringent requirements of process chemistry and research applications. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Potassium Content	14.0 - 16.0 %
Solubility	Soluble in THF, DMF; reacts with protic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.