Description

2-Diazo-3-Trifluoropropionyloxy Geranyl Pyrophosphate is a specialized, high-value biochemical intermediate featuring a unique diazo and trifluoropropionyloxy functionalized geranyl pyrophosphate backbone. This compound is critical for advanced research and synthesis in medicinal chemistry, particularly for the development of novel enzyme inhibitors and mechanism-based probes. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating next-generation therapeutics and agrochemicals.

Application

• Mechanism-Based Enzyme Inhibition: Serves as a key precursor for synthesizing potent, irreversible inhibitors targeting prenyltransferases and related enzymes in metabolic pathway studies.
• Medicinal Chemistry Probe Development: Used in the design and synthesis of bioactive probes for investigating protein prenylation and signal transduction mechanisms.
• Agrochemical Research: Employed in the discovery of novel plant growth regulators and herbicides that interfere with specific isoprenoid biosynthesis pathways.
• Isotope-Labeled Compound Synthesis: Acts as a starting material for preparing carbon-13 or tritium-labeled analogs for pharmacokinetic and metabolic tracing studies.
• Chemical Biology Tool: Facilitates the study of terpenoid biosynthesis and protein lipidation processes in cellular models.

Basic Information

Product Name	2-Diazo-3-Trifluoropropionyloxy Geranyl Pyrophosphate
CAS No.	88887-99-4
Molecular Formula	C15H22F3N2O9P2
Molecular Weight	502.29 g/mol
Synonyms	Geranyl Pyrophosphate 2-Diazo-3-Trifluoropropionate; 2-Diazo-3-(trifluoropropionyloxy)geranyl diphosphate; (2E,6E)-3,7-Dimethylocta-2,6-dien-1-yl (1-diazo-3,3,3-trifluoro-1-oxopropan-2-yl) dihydrogen diphosphate; GPP Diazo Trifluoropropionyl Ester; 2-Diazo-1-(geranyloxyphosphonooxy)-3,3,3-trifluoropropan-1-one
EINECS	Contact for details

Quality Control

Every batch of 2-Diazo-3-Trifluoropropionyloxy Geranyl Pyrophosphate is manufactured under strict quality protocols and undergoes comprehensive analytical characterization to ensure identity, purity, and stability. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from NMR (1H, 13C, 19F, 31P), HPLC, and mass spectrometry. Our quality management system supports cGMP-compliant production for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (argon or nitrogen) in a dedicated freezer. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong acids/bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.