Description

2-Azaspiro[4.5]Decane-3-Carboxylic Acid, Hydrochloride is a high-purity, nitrogen-containing spirocyclic compound supplied as its hydrochloride salt. This specialized building block is valued for its rigid, three-dimensional structure, which is crucial for modulating the physicochemical properties and biological activity of target molecules in advanced research. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, particularly in medicinal chemistry for central nervous system (CNS) and other therapeutic targets.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in neurological and psychiatric disorder research.
• Medicinal Chemistry: Used to introduce a constrained spirocyclic scaffold into molecules to improve potency, selectivity, and metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with novel modes of action.
• Chemical Biology: Employed as a probe or ligand in the study of enzyme inhibition and receptor binding.
• Academic & Contract Research: Used in universities and CROs for method development and exploratory synthesis projects.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value fine chemicals and APIs.

Basic Information

Product Name	2-Azaspiro[4.5]Decane-3-Carboxylic Acid, Hydrochloride
CAS No.	88578-97-6
Molecular Formula	C10H18ClNO2
Molecular Weight	219.71 g/mol
Synonyms	2-Azaspiro[4.5]decane-3-carboxylic acid hydrochloride; 3-Carboxy-2-azaspiro[4.5]decane hydrochloride; 2-Azaspiro[4.5]decane-3-carboxylic acid HCl; 1-Azaspiro[4.5]decane-2-carboxylic acid hydrochloride (tautomer); Spiro[cyclohexane-1,3'-pyrrolidine]-2'-carboxylic acid hydrochloride; 88578-97-6; 2-Azaspiro[4.5]decan-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Azaspiro[4.5]Decane-3-Carboxylic Acid, Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) including HPLC purity, chiral purity (where applicable), and identification data is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.