Description

2-Chloro-4-Fluorobenzotrichloride is a versatile and highly reactive halogenated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in the presence of multiple chlorine atoms on the benzylic carbon, making it a key precursor for the production of various agrochemicals, pharmaceuticals, and specialty chemicals. This compound is primarily needed by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical manufacturing industries.

Application

• Agrochemical Intermediate: A critical building block for the synthesis of advanced herbicides, fungicides, and insecticides.
• Pharmaceutical Synthesis: Serves as a key precursor in the development of active pharmaceutical ingredients (APIs), particularly those with fluorinated and chlorinated aromatic systems.
• Liquid Crystal & OLED Material Production: Used in the manufacture of fluorinated components for electronic display materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating complex, halogenated organic dyes and pigments.
• Polymer Modification: Employed to introduce functional groups into polymer chains for enhanced material properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions like Suzuki and Negishi couplings for constructing complex biaryl structures.

Basic Information

Product Name	2-Chloro-4-Fluorobenzotrichloride
CAS No.	88578-92-1
Molecular Formula	C7H2Cl4F
Molecular Weight	246.90 g/mol
Synonyms	2-Chloro-4-fluorobenzotrichloride; 1-(Trichloromethyl)-2-chloro-4-fluorobenzene; α,α,α-Trichloro-2-chloro-4-fluorotoluene; 2-Chloro-4-fluoro-α,α,α-trichlorotoluene; Benzene, 1-(trichloromethyl)-2-chloro-4-fluoro-; 2-Chloro-4-fluorophenyltrichloromethane; (2-Chloro-4-fluorophenyl)trichloromethane
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorobenzotrichloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR for verification. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.