Description

2-Chloro-4-Fluorobenzamide is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine substituents modulate bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and the development of molecular probes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-4-Fluorobenzamide
CAS No.	88578-90-9
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	2-Chloro-4-fluorobenzoic acid amide; Benzoamide, 2-chloro-4-fluoro-; 4-Fluoro-2-chlorobenzamide; 2-Chloro-4-fluorobenzamide; 88578-90-9; 2-Chloro-4-fluorobenzenecarboxamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluorobenzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.