Description

Ethyl 7-Chloro-6-Fluoro-1-(Formylamino)-1,4-Dihydro-4-Oxoquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of novel fluoroquinolone antibiotics, enabling the development of next-generation antimicrobial agents. It is primarily required by pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) manufacturers targeting complex, high-value therapeutic applications.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a core precursor in the synthesis of potent antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and optimization of new drug candidates with improved efficacy.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in scaled-up production processes for final drug substances.
• Chemical Synthesis Studies: Utilized in academic and industrial research to explore novel synthetic pathways and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	Ethyl 7-Chloro-6-Fluoro-1-(Formylamino)-1,4-Dihydro-4-Oxoquinoline-3-Carboxylate
CAS No.	88569-33-9
Molecular Formula	C₁₃H₁₀ClFN₂O₄
Molecular Weight	312.68 g/mol
Synonyms	7-Chloro-6-fluoro-1-(formylamino)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester; Ethyl 1-formylamino-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate; 1-Formylamino-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 88569-33-9; Intermediate for Fluoroquinolone Antibiotics; Quinolone Carboxylate Ester Derivative
EINECS	Contact for details

Quality Control

Our Ethyl 7-Chloro-6-Fluoro-1-(Formylamino)-1,4-Dihydro-4-Oxoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.