Description

8-(Bromomethyl)-5-Chloroquinoline is a versatile halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its bifunctional reactivity, where the bromomethyl group offers a handle for alkylation or further functionalization, and the chloroquinoline core provides a privileged pharmacophore. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, including potential active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing new crop protection agents and pesticides that leverage the bioactivity of the quinoline scaffold.
• Material Science Research: Used in the creation of organic ligands for catalysis or functional materials due to its modifiable structure.
• Chemical Biology Probes: Serves as a starting point for synthesizing fluorescent tags or molecular probes for biological target identification.
• Cross-Coupling Reactions: The bromomethyl moiety makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Academic & R&D: Fundamental research reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	8-(Bromomethyl)-5-Chloroquinoline
CAS No.	88474-19-5
Molecular Formula	C10H7BrClN
Molecular Weight	256.52 g/mol
Synonyms	5-Chloro-8-(bromomethyl)quinoline; 5-Chloro-8-quinolinemethyl bromide; 8-Bromomethyl-5-chloroquinoline; (5-Chloro-8-quinolyl)methyl bromide; 88474-19-5; 8-(Bromomethyl)-5-chloro-quinoline; 5-Chloro-8-bromomethylquinoline
EINECS	Contact for details

Quality Control

Our 8-(Bromomethyl)-5-Chloroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.