Description

1H-Cyclopenta[B]Benzofuran-5-Butanoic Acid, 2-(Acetyloxy)-2,3,3A,8B-Tetrahydro-1-(Hydroxymethyl)-, Methyl Ester, (1S,2R,3As,8Bs)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) due to its specific chiral configuration and functional groups. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in specialized organic synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex, biologically active molecules and proprietary APIs.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing intricate polycyclic frameworks and studying stereoselective reactions.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes from laboratory to pilot and commercial production.
• Chiral Synthesis: Utilized in the preparation of enantiomerically pure compounds for pharmaceutical and agrochemical applications.
• Medicinal Chemistry: Employed in the design and synthesis of new chemical entities for biological screening and drug discovery programs.

Basic Information

Item	Details
Product Name	1H-Cyclopenta[B]Benzofuran-5-Butanoic Acid, 2-(Acetyloxy)-2,3,3A,8B-Tetrahydro-1-(Hydroxymethyl)-, Methyl Ester, (1S,2R,3As,8Bs)-
CAS No.	88295-11-8
Molecular Formula	C19H24O6
Molecular Weight	348.39 g/mol
Synonyms	(1S,2R,3aS,8bS)-2-(Acetyloxy)-2,3,3a,8b-tetrahydro-1-(hydroxymethyl)-1H-cyclopenta[b]benzofuran-5-butanoic acid methyl ester; Methyl (1S,2R,3aS,8bS)-2-(acetyloxy)-1-(hydroxymethyl)-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-5-butanoate; CAS 88295-11-8; 1H-Cyclopenta[b]benzofuran-5-butanoic acid, 2-(acetyloxy)-2,3,3a,8b-tetrahydro-1-(hydroxymethyl)-, methyl ester, (1S,2R,3aS,8bS)-; Advanced Benzofuran Intermediate; Chiral Cyclopentabenzofuran Ester.
EINECS	Contact for details

Quality Control

Our 1H-Cyclopenta[B]Benzofuran-5-Butanoic Acid, 2-(Acetyloxy)-2,3,3A,8B-Tetrahydro-1-(Hydroxymethyl)-, Methyl Ester, (1S,2R,3As,8Bs)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for demanding pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.