Description

5-Fluoro-6-Methoxyquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both fluorine and methoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and pesticides, where the quinoline core contributes to biological activity.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and other electronic materials due to its conjugated structure.
• Chemical Biology & Proteomics: Employed as a fluorescent tag or a core structure in the design of molecular probes and enzyme inhibitors.
• Catalyst Ligand Development: The nitrogen atom provides a coordination site for metals, making it useful in designing novel catalytic systems.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and functionalization reactions.

Basic Information

Product Name	5-Fluoro-6-Methoxyquinoline
CAS No.	88288-04-4
Molecular Formula	C₁₀H₈FNO
Molecular Weight	177.18 g/mol
Synonyms	6-Methoxy-5-fluoroquinoline; Quinoline, 5-fluoro-6-methoxy-; 5-Fluoro-6-methoxy-quinoline; 5-Fluoro-6-methoxy-chinolin; 88288-04-4 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methoxyquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), our technical team is available to discuss your requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.