Description

Methyl 2-Azabicyclo[2.2.1]Heptane-3-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant intermediate featuring a rigid bicyclic scaffold. This compound matters as a versatile chiral building block for the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily needed by research organizations and pharmaceutical companies developing new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates.
• Medicinal Chemistry: Used to construct constrained analogs and explore structure-activity relationships (SAR) in drug discovery programs.
• Asymmetric Synthesis: Serves as a precursor for catalysts or ligands used in stereoselective transformations.
• Chemical Biology: Employed as a probe or scaffold in the study of biological targets and pathways.
• Process Chemistry: Investigated for scalable routes to advanced intermediates under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in synthetic organic chemistry studies focused on novel heterocyclic systems.

Basic Information

Product Name	Methyl 2-Azabicyclo[2.2.1]Heptane-3-Carboxylate Hydrochloride
CAS No.	88259-98-7
Molecular Formula	C8H14ClNO2
Molecular Weight	191.66 g/mol
Synonyms	Methyl 2-azabicyclo[2.2.1]heptane-3-carboxylate HCl; 3-Carbomethoxy-2-azabicyclo[2.2.1]heptane hydrochloride; 2-Azanorbornane-3-carboxylic acid methyl ester hydrochloride; Methyl endo-2-azabicyclo[2.2.1]heptane-3-carboxylate hydrochloride; Methyl 2-azanorbornane-3-carboxylate HCl
EINECS	Contact for details

Quality Control

Our Methyl 2-Azabicyclo[2.2.1]Heptane-3-Carboxylate Hydrochloride is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.