Description

4-Hydroxymethylbenz(A)Anthracene-8,9-Dihydrodiol is a high-purity, specialized polycyclic aromatic hydrocarbon (PAH) derivative, specifically a dihydrodiol metabolite. This compound matters as a critical reference standard and research chemical for toxicological and metabolic studies, enabling precise analysis of PAH activation pathways. It is primarily needed by pharmaceutical R&D laboratories, environmental testing facilities, and academic research institutions focused on carcinogenesis, mutagenicity, and metabolic profiling.

Application

• Biochemical Research: Used as a metabolite standard in studies investigating the metabolic activation and detoxification pathways of benz(a)anthracene and related polycyclic aromatic hydrocarbons (PAHs).
• Toxicology & Carcinogenicity Studies: Serves as a key intermediate reference material for assessing the genotoxic and carcinogenic potential of PAHs in in vitro and in vivo models.
• Analytical Method Development: Employed as a certified reference material (CRM) for calibrating analytical instruments like HPLC, GC-MS, and LC-MS in environmental and biological monitoring.
• Environmental Science: Acts as a standard for quantifying PAH metabolites in samples from occupational exposure, pollution studies, and ecological risk assessments.
• Drug Metabolism & Pharmacokinetics (DMPK): Utilized in pharmaceutical research to understand the bioactivation of drug candidates with PAH-like structures.

Basic Information

Product Name	4-Hydroxymethylbenz(A)Anthracene-8,9-Dihydrodiol
CAS No.	88195-59-9
Molecular Formula	C21H18O3
Molecular Weight	318.37 g/mol
Synonyms	4-(Hydroxymethyl)benz[a]anthracene-8,9-dihydrodiol; 8,9-Dihydro-8,9-dihydroxy-4-(hydroxymethyl)benz[a]anthracene; 4-HMBA-8,9-diol; Benz[a]anthracene-4-methanol, 8,9-dihydro-8,9-dihydroxy-; 4-Hydroxymethylbenz[a]anthracene-8,9-dihydrodiol; 4-HMBA-dihydrodiol; 4-Hydroxymethyl-BA-8,9-dihydrodiol
EINECS	Contact for details

Quality Control

Our 4-Hydroxymethylbenz(A)Anthracene-8,9-Dihydrodiol is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and analytical methods is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.