Description

(2R,6Aβ,10Bβ)-8α-Acetyloxy-3α-Ethenyldodecahydro-3,4Aα,7,7,10Aα-Pentamethyl-1H-Naphtho[2,1-B]Pyran-2β-Ol CAS NO 88143-06-0 is a high-purity, complex diterpenoid derivative characterized by its specific stereochemistry and functional groups. This compound is of significant interest for its potential as a key chiral intermediate or reference standard in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates, particularly in steroid or terpenoid-based therapeutic areas.
• Reference Standard: Used as a high-purity analytical standard for method development, quality control, and regulatory compliance in pharmaceutical analysis.
• Asymmetric Synthesis: Employed in advanced organic synthesis to introduce complex stereocenters and molecular frameworks due to its defined (2R,6Aβ,10Bβ) configuration.
• Natural Product Research: Acts as a synthetic analog or derivative for studying structure-activity relationships (SAR) of bioactive natural products.
• Agrochemical Development: Potential intermediate in the research and synthesis of new, high-specificity plant protection agents.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new chemical spaces and reaction methodologies.

Basic Information

Item	Details
Product Name	(2R,6Aβ,10Bβ)-8α-Acetyloxy-3α-Ethenyldodecahydro-3,4Aα,7,7,10Aα-Pentamethyl-1H-Naphtho[2,1-B]Pyran-2β-Ol
CAS No.	88143-06-0
Molecular Formula	C24H38O4
Molecular Weight	390.56 g/mol
Synonyms	8α-Acetoxy-3α-vinyldodecahydro-3,4aα,7,7,10aα-pentamethyl-1H-naphtho[2,1-b]pyran-2β-ol; Labdane diterpenoid derivative; (2R,6aβ,10bβ)-8α-Acetyloxy-3α-ethenyldodecahydro-3,4aα,7,7,10aα-pentamethyl-1H-naphtho[2,1-b]pyran-2β-ol; 88143-06-0; Acetylated labdane alcohol; Vinyl labdane derivative
EINECS	Contact for details

Quality Control

Our (2R,6Aβ,10Bβ)-8α-Acetyloxy-3α-Ethenyldodecahydro-3,4Aα,7,7,10Aα-Pentamethyl-1H-Naphtho[2,1-B]Pyran-2β-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and purity meet rigorous research-grade specifications. A detailed Certificate of Analysis (COA) providing batch-specific results for assay, related substances, and chiral purity is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.