Description

1-Bromomethyl-2-[(Phenylsulfonyl)Methyl]Benzene is a specialized organic building block featuring both bromomethyl and phenylsulfonylmethyl functional groups on a benzene ring. This unique bifunctional structure makes it a valuable intermediate for constructing complex molecules in advanced synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific aromatic sulfone architectures.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, or organic electronic materials where the sulfone group imparts thermal stability and polarity.
• Cross-Coupling Reactions: The bromomethyl moiety acts as an electrophilic site for various palladium-catalyzed or nucleophilic substitution reactions to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands or organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Can be employed to create molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	1-Bromomethyl-2-[(Phenylsulfonyl)Methyl]Benzene
CAS No.	88116-02-3
Molecular Formula	C15H15BrO2S
Molecular Weight	339.25 g/mol
Synonyms	2-(Bromomethyl)-1-[(phenylsulfonyl)methyl]benzene; 1-(Bromomethyl)-2-((phenylsulfonyl)methyl)benzene; α-Bromo-o-xylene-α'-phenylsulfone; (2-Bromomethylbenzyl) phenyl sulfone; Benzene, 1-bromomethyl-2-[(phenylsulfonyl)methyl]-; o-Bromomethylbenzyl phenyl sulfone
EINECS	Contact for details

Quality Control

Our 1-Bromomethyl-2-[(Phenylsulfonyl)Methyl]Benzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and meet the stringent requirements of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.