Description

1H-Cyclopentcisoxazole-3,4,5,6-Tetrol, Hexahydro-1-Methyl-, Tetraacetate (Ester), 3R-(3.Alpha.,3A.Alpha.,4.Alpha.,5.Beta.,6.Alpha.,6A.Alpha.)- is a complex, high-purity organic intermediate with a defined stereochemistry. This compound is valued for its role as a key chiral building block in sophisticated synthetic pathways, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of complex drug molecules, especially those targeting neurological or metabolic diseases.
• Organic Synthesis Building Block: Used in academic and industrial research laboratories for constructing novel heterocyclic compounds and exploring new chemical spaces.
• Process Chemistry Development: Employed in scaling up synthetic routes from milligram to kilogram scale, where its defined stereochemistry ensures batch-to-batch consistency.
• Asymmetric Catalysis Research: Acts as a substrate or ligand precursor in studies aimed at developing new stereoselective catalytic reactions.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	1H-Cyclopentcisoxazole-3,4,5,6-Tetrol, Hexahydro-1-Methyl-, Tetraacetate (Ester), 3R-(3.Alpha.,3A.Alpha.,4.Alpha.,5.Beta.,6.Alpha.,6A.Alpha.)-
CAS No.	88111-89-1
Molecular Formula	C14H19NO9
Molecular Weight	345.30 g/mol
Synonyms	1-Methyl-1H-cyclopenta[d]isoxazole-3,4,5,6-tetrol, hexahydro-, tetraacetate (ester), (3R,3aS,4R,5S,6R,6aS)-; Hexahydro-1-methyl-1H-cyclopenta[d]isoxazole-3,4,5,6-tetrol tetraacetate; (3R,3aS,4R,5S,6R,6aS)-Hexahydro-1-methyl-1H-cyclopenta[d]isoxazole-3,4,5,6-tetrol tetraacetate; Cyclopentisoxazole tetraacetate derivative; Chiral cyclopentisoxazole intermediate; 1-Methylcyclopentisoxazole tetraacetate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, enantiomeric excess, and impurity profiles. We support cGMP compliance for pharmaceutical applications, with documentation tailored to meet rigorous audit standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.