Description

(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(3-Methylbutanoyloxy)Oxane-2 Carboxylic Acid is a high-purity, stereochemically defined derivative of glucuronic acid, valued for its role as a key chiral building block and metabolic intermediate. Its precise stereochemistry and functional groups make it a critical intermediate for advanced pharmaceutical synthesis, particularly in the development of glycosidase inhibitors and prodrugs. This compound is essential for research and production in fine chemical, pharmaceutical R&D, and advanced material science sectors where specific molecular conformation dictates biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of complex drug molecules, especially glycosidase inhibitors and antiviral agents.
• Biochemical Research: Used as a standard or substrate in enzymatic studies related to carbohydrate metabolism and conjugation pathways.
• Prodrug Development: Serves as a promoiety for designing prodrugs to enhance drug solubility, stability, or targeted delivery.
• Fine Chemical Synthesis: Employed in asymmetric synthesis to introduce specific sugar-based motifs into complex organic molecules.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Item	Details
Product Name	(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(3-Methylbutanoyloxy)Oxane-2 Carboxylic Acid
CAS No.	88070-93-3
Molecular Formula	C12H18O9
Molecular Weight	306.27 g/mol
Synonyms	3,4,5-Trihydroxy-6-[(3-methyl-1-oxobutoxy)]oxane-2-carboxylic acid; D-Glucuronic acid, 6-(3-methylbutanoate); 6-O-Isovaleryl-D-glucuronic acid; Isovaleryl glucuronic acid; (2S,3S,4S,5R,6S)-6-[(3-Methylbutanoyl)oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid; Glucuronate isovalerate ester
EINECS	Contact for details

Quality Control

Our (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(3-Methylbutanoyloxy)Oxane-2 Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccants or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.