Description

(1S,4Z,6S,11R)-4,7,7,11-Tetramethyl-12-Oxabicyclo[9.1.0]Dodec-4-En-6-Ol is a high-purity, stereochemically defined oxabicyclic compound that serves as a valuable chiral intermediate and building block in advanced organic synthesis. Its unique, rigid molecular framework makes it a critical precursor for the development of complex molecules with specific three-dimensional architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for applications in asymmetric synthesis, fragrance development, and the creation of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, especially those requiring specific stereochemistry for biological activity.
• Asymmetric Synthesis: Utilized as a starting material or catalyst ligand in stereoselective reactions to create enantiomerically pure compounds.
• Fragrance and Flavor Chemistry: Serves as a precursor for the synthesis of novel, high-value odorants and flavorants with unique organoleptic properties.
• Agrochemical Research: Used in the development of new, stereospecific active ingredients for crop protection products.
• Material Science: Acts as a monomer or cross-linking agent for creating polymers with specialized optical or mechanical properties.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	(1S,4Z,6S,11R)-4,7,7,11-Tetramethyl-12-Oxabicyclo[9.1.0]Dodec-4-En-6-Ol
CAS No.	87989-23-9
Molecular Formula	C₁₅H₂₆O₂
Molecular Weight	238.37 g/mol
Synonyms	12-Oxabicyclo[9.1.0]dodec-4-ene-6-ol, 4,7,7,11-tetramethyl-, (1S,4Z,6S,11R)-; Ambrosanol; (1S,4Z,6S,11R)-4,7,7,11-Tetramethyl-12-oxabicyclo[9.1.0]dodec-4-en-6-ol; (-)-Ambrox; (1S,4Z,6S,11R)-Ambrox; (1S-(1alpha,4Z,6alpha,11R*))-4,7,7,11-Tetramethyl-12-oxabicyclo[9.1.0]dodec-4-en-6-ol; Chiral Ambroxan precursor; Stereoisomer of Ambrox.
EINECS	Contact for details

Quality Control

Our (1S,4Z,6S,11R)-4,7,7,11-Tetramethyl-12-Oxabicyclo[9.1.0]Dodec-4-En-6-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including chiral HPLC, GC, and NMR, to verify identity, stereochemical purity, and chemical composition. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.