Description

(R)-α,α,5,6-Tetramethyl-1,2,3,4-Tetrahydronaphthalene-2-Methanol is a high-purity, chiral organic compound characterized by its specific stereochemistry and complex tetrahydronaphthalene backbone. This compound matters as a sophisticated chiral building block and key intermediate for the synthesis of advanced molecules, where its defined stereocenter is critical for biological activity and material properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by fine chemical manufacturers focused on creating novel fragrances, flavors, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a building block for creating novel pesticides and herbicides with enhanced efficacy and stereospecificity.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthesizing complex, musky, or woody aroma chemicals due to its tetralin structure.
• Material Science Research: Investigated as a monomer or dopant for the development of advanced organic electronic materials and liquid crystals.
• Asymmetric Catalysis: Employed as a chiral ligand or auxiliary in stereoselective synthesis to control the outcome of chemical reactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in organic synthesis.

Basic Information

Item	Details
Product Name	(R)-α,α,5,6-Tetramethyl-1,2,3,4-Tetrahydronaphthalene-2-Methanol
CAS No.	87797-89-5
Molecular Formula	C₁₅H₂₂O
Molecular Weight	218.33 g/mol
Synonyms	(R)-2-(Hydroxymethyl)-α,α,5,6-tetramethyl-1,2,3,4-tetrahydronaphthalene; (2R)-α,α,5,6-Tetramethyl-1,2,3,4-tetrahydronaphthalene-2-methanol; (R)-α,α,5,6-Tetramethyl-2-naphthalenemethanol, 1,2,3,4-tetrahydro-; Tetralin derivative, chiral; Chiral tetralin methanol; (R)-Tetrahydronaphthalenemethanol derivative
EINECS	Contact for details

Quality Control

Our (R)-α,α,5,6-Tetramethyl-1,2,3,4-Tetrahydronaphthalene-2-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess and standard purity assays, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed specifications for identity, purity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.