Description

1H,5H-Benzo[Ij]Quinolizine-2-Carboxylic Acid, 8-Amino-9-Fluoro-6,7-Dihydro-5-Methyl-1-Oxo- is a high-purity, complex heterocyclic carboxylic acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for building complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its unique fluorinated benzoquinolizine structure.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in custom synthesis and process development.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Production: Acts as a specialized substrate for introducing fluorine-containing motifs into target molecules, a valuable trait in modern drug design.

Basic Information

Product Name	1H,5H-Benzo[Ij]Quinolizine-2-Carboxylic Acid, 8-Amino-9-Fluoro-6,7-Dihydro-5-Methyl-1-Oxo-
CAS No.	87488-29-7
Molecular Formula	C15H15FN2O3
Molecular Weight	290.29 g/mol
Synonyms	8-Amino-9-fluoro-5-methyl-6,7-dihydro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid; 8-Amino-9-fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydrobenzo[ij]quinolizine-2-carboxylic acid; 87488-29-7; Benzo[ij]quinolizine-2-carboxylic acid, 8-amino-9-fluoro-6,7-dihydro-5-methyl-1-oxo-; 9-Fluoro-8-amino-5-methyl-1-oxo-1,5,6,7-tetrahydrobenzo[ij]quinolizine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1H,5H-Benzo[Ij]Quinolizine-2-Carboxylic Acid, 8-Amino-9-Fluoro-6,7-Dihydro-5-Methyl-1-Oxo- adheres to stringent quality management protocols. All batches undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.