Description

3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a trifluoromethyl group on the pyridine ring, makes it indispensable for creating molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Building block for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid
CAS No.	87407-12-3
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)picolinic acid; 3-Trifluoromethylpyridine-2-carboxylic acid; 3-TFM-PCA; 2-Carboxy-3-(trifluoromethyl)pyridine; α,α,α-Trifluoro-3-picolinic acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.