Description

8-(Bromomethyl)-6-Chloroquinoline is a versatile halogenated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both bromomethyl and chloro substituents, makes it a valuable electrophilic building block for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with quinoline-based scaffolds.
• Material Science Research: Used in the creation of organic semiconductors, ligands for catalysis, and advanced functional polymers.
• Chemical Biology Probes: Serves as a starting material for synthesizing fluorescent tags or affinity probes due to the modifiable bromomethyl group.
• Cross-Coupling Reactions: The bromomethyl moiety is reactive in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Nucleophilic Substitution: The halogenated sites allow for further functionalization with various nucleophiles to create diverse chemical libraries.

Basic Information

Item	Details
Product Name	8-(Bromomethyl)-6-Chloroquinoline
CAS No.	87293-40-1
Molecular Formula	C10H7BrClN
Molecular Weight	256.52 g/mol
Synonyms	6-Chloro-8-(bromomethyl)quinoline; 8-Bromomethyl-6-chloroquinoline; Quinoline, 8-(bromomethyl)-6-chloro-; 6-Chloro-8-quinolinemethyl bromide; 8-(Bromomethyl)-6-chloro-quinoline
EINECS	Contact for details

Quality Control

Our 8-(Bromomethyl)-6-Chloroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.