Description

6-Piperazino-1,2,3,4-Tetrahydroquinoline-2-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and manufacturing who require reliable, high-quality intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and process chemistry for potential APIs, especially in the CNS therapeutic area.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and new synthetic methodology development.

Basic Information

Product Name	6-Piperazino-1,2,3,4-Tetrahydroquinoline-2-One
CAS No.	87154-95-8
Molecular Formula	C₁₃H₁₇N₃O
Molecular Weight	231.30 g/mol
Synonyms	6-(Piperazin-1-yl)-1,2,3,4-tetrahydroquinolin-2-one; 2-Oxo-6-piperazino-1,2,3,4-tetrahydroquinoline; 6-Piperazino-3,4-dihydro-2(1H)-quinolinone; 87154-95-8; Tetrahydroquinolinone piperazine derivative
EINECS	Contact for details

Quality Control

Our 6-Piperazino-1,2,3,4-Tetrahydroquinoline-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) documenting all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.