Description

2-(2-Chloro-2-Nitropropoxy)Tetrahydro-2H-Pyran is a specialized organic compound featuring a unique molecular scaffold combining a nitroalkane and a tetrahydropyranyl ether group. This structure makes it a valuable intermediate in synthetic organic chemistry, particularly for the construction of complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for use in multi-step synthesis, where it can serve as a protected alcohol precursor or a nitroalkylating agent.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring nitro or amino functional groups.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive nitro and chloro sites.
• Organic Synthesis Research: Serves as a versatile reagent in academic and industrial R&D for constructing heterocyclic compounds and complex molecular architectures.
• Material Science Precursor: Potential intermediate in the development of specialty polymers and fine chemicals requiring specific ether linkages.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening for generating diverse compound libraries for biological testing.

Basic Information

Product Name	2-(2-Chloro-2-Nitropropoxy)Tetrahydro-2H-Pyran
CAS No.	86958-48-7
Molecular Formula	C8H14ClNO4
Molecular Weight	223.65 g/mol
Synonyms	2-(2-Chloro-2-nitropropoxy)tetrahydro-2H-pyran; 2-(2-Chloro-2-nitropropoxy)oxane; 2-(2-Chloro-2-nitropropoxy)tetrahydropyran; THP ether of 2-chloro-2-nitro-1-propanol; 1-(Tetrahydro-2H-pyran-2-yloxy)-2-chloro-2-nitropropane; 2-Chloro-2-nitropropyl tetrahydropyranyl ether; 86958-48-7; 2-(2-Chloro-2-nitro-propoxy)-tetrahydropyran
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-2-Nitropropoxy)Tetrahydro-2H-Pyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.