Description

(S)-1,1''-Binaphthalene-2,2''-Diiodo ((S)-2,2''-Diiodo-1''1-Binaphthyl) CAS NO 86688-07-5 is a high-value, enantiomerically pure chiral building block and ligand precursor. This compound is critical for enabling asymmetric synthesis in advanced pharmaceutical and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex, optically active molecules.

Application

• Chiral Ligand Synthesis: A key precursor for synthesizing BINOL-derived phosphoric acids, phosphines, and N-oxides used in asymmetric catalysis.
• Pharmaceutical Intermediates: Enables the construction of chiral backbones for active pharmaceutical ingredients (APIs) targeting CNS disorders, oncology, and infectious diseases.
• Asymmetric Catalysis: Serves as a starting material for developing novel chiral catalysts for C-C and C-X bond-forming reactions.
• Material Science: Used in the development of chiral organic frameworks, liquid crystals, and polymers with specific optical properties.
• Agrochemical Research: Employed in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A fundamental tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(S)-1,1''-Binaphthalene-2,2''-Diiodo ((S)-2,2''-Diiodo-1''1-Binaphthyl)
CAS No.	86688-07-5
Molecular Formula	C₂₀H₁₂I₂
Molecular Weight	546.12 g/mol
Synonyms	(S)-2,2'-Diiodo-1,1'-binaphthyl; (S)-BINOL-2,2'-diiodide; (S)-1,1'-Bi-2-naphthol-2,2'-diiodo derivative; (S)-2,2'-Diiodo-[1,1'-binaphthalene]-4,4'-diol (precursor form); (S)-BINAP diiodo precursor; (S)-VAPOL diiodo precursor; (S)-2,2'-Diiodo-1,1'-binaphthyl-4,4'-diol; (S)-DIB
EINECS	Contact for details

Quality Control

Our (S)-1,1''-Binaphthalene-2,2''-Diiodo is manufactured under strict quality protocols to ensure high enantiomeric excess (ee) and chemical purity, critical for sensitive asymmetric transformations. Each batch is characterized by chiral HPLC, NMR, and elemental analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and full analytical data are provided to guarantee reproducible performance in your synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.