Description

R-1,1'-Binaphthalene-2,2'-Diiodo is a high-purity, chiral binaphthyl derivative characterized by iodine substitution at the 2 and 2' positions, serving as a critical synthetic intermediate. This compound matters for its role as a versatile building block in asymmetric synthesis and as a precursor for chiral ligands and catalysts. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral active pharmaceutical ingredients (APIs) and diagnostic agents.
• Chiral Ligand Synthesis: Used to prepare binaphthyl-based phosphines and N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Material Science Research: Building block for chiral organic frameworks, polymers, and liquid crystals with specific optical properties.
• Cross-Coupling Reactions: Serves as an electrophilic coupling partner in Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl systems.
• Asymmetric Catalysis Development: Fundamental starting material for developing and screening new chiral catalysts.
• Agrochemical Synthesis: Intermediate in the production of enantiomerically pure herbicides and fungicides.

Basic Information

Product Name	R-1,1'-Binaphthalene-2,2'-Diiodo
CAS No.	86688-06-4
Molecular Formula	C20H12I2
Molecular Weight	506.12 g/mol
Synonyms	(R)-2,2'-Diiodo-1,1'-binaphthyl; (R)-1,1'-Bi-2-naphthol Diiodide; (R)-BINOL-Diiodo; (R)-2,2'-Diiodo-[1,1'-binaphthalene]; (R)-BINAP-I2; R-BINOL-2,2'-diiodide; (R)-1,1'-Binaphthyl-2,2'-diyl diiodide; (R)-DIB
EINECS	Contact for details

Quality Control

Our R-1,1'-Binaphthalene-2,2'-Diiodo is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided, confirming identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.