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R-2,2'-Bis(Bromomethyl)-1,1'-Binaphthalene CAS NO 86631-56-3


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CAS No.:86631-56-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

R-2,2'-Bis(Bromomethyl)-1,1'-Binaphthalene is a chiral, axially-disymmetric organic building block of significant synthetic utility. This compound is valued for its role as a key precursor in the synthesis of sophisticated chiral ligands and catalysts, particularly for asymmetric transformations. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing enantioselective processes.

Application

  • Chiral Ligand Synthesis: A crucial precursor for constructing BINOL and BINAP derivative ligands used in asymmetric catalysis.
  • Pharmaceutical Intermediates: Serves as a building block for active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
  • Asymmetric Catalyst Development: Used in the research and production of organocatalysts and metal-complex catalysts for enantioselective synthesis.
  • Advanced Material Research: Employed in the development of chiral polymers, liquid crystals, and molecular recognition systems.
  • Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is critical for activity.
  • Academic & Industrial R&D: A valuable reagent for methodological studies in organic and organometallic chemistry.

Basic Information

Product Name R-2,2'-Bis(Bromomethyl)-1,1'-Binaphthalene
CAS No. 86631-56-3
Molecular Formula C22H16Br2
Molecular Weight 440.17 g/mol
Synonyms (R)-2,2'-Bis(bromomethyl)-1,1'-binaphthalene; (R)-2,2'-Bis(bromomethyl)-1,1'-binaphthyl; (R)-BINOL-Br; (R)-1,1'-Binaphthalene-2,2'-dimethanol, 2,2'-bis(bromomethyl)-, (R)-; (R)-2,2'-Dibromomethyl-1,1'-binaphthyl; R-BINOL-(CH2Br)2; (R)-BINOL-DiBr
EINECS Contact for details

Quality Control

Our R-2,2'-Bis(Bromomethyl)-1,1'-Binaphthalene is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques, including chiral HPLC to confirm enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Melting Point Contact for details
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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