Description

4-((4-Bromophenyl)Hydroxymethyl)-3-Methyl-1-Oxaspiro(4.5)Dec-3-En-2-On E is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and brominated aromatic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development for therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating complex, high-value molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex spirocyclic frameworks and studying structure-activity relationships (SAR).
• Agrochemical Development: Potential intermediate in the research and synthesis of new generation pesticides or herbicides due to its brominated aromatic moiety.
• Material Science Precursor: Serves as a specialized monomer or precursor in the development of advanced organic materials and functional polymers.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Item	Details
Product Name	4-((4-Bromophenyl)Hydroxymethyl)-3-Methyl-1-Oxaspiro(4.5)Dec-3-En-2-On E
CAS No.	86560-18-1
Molecular Formula	C18H21BrO3
Molecular Weight	365.26 g/mol
Synonyms	4-[(4-Bromophenyl)(hydroxy)methyl]-3-methyl-1-oxaspiro[4.5]dec-3-en-2-one; 3-Methyl-4-((4-bromophenyl)hydroxymethyl)-1-oxaspiro[4.5]dec-3-en-2-one; 1-Oxaspiro[4.5]dec-3-en-2-one, 4-((4-bromophenyl)hydroxymethyl)-3-methyl-; 86560-18-1; Bromophenyl hydroxymethyl methyl oxaspirodecenone; Spirocyclic bromo intermediate
EINECS	Contact for details

Quality Control

Our production of 4-((4-Bromophenyl)Hydroxymethyl)-3-Methyl-1-Oxaspiro(4.5)Dec-3-En-2-On E adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects requiring material manufactured under cGMP guidelines and can provide documentation to meet regulatory submission standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.