Description

1-Oxaspiro(4.5)Dec-3-En-2-One, 4-((4-Fluorophenyl)Hydroxymethyl)-3-Methyl- is a high-value, fluorinated spirocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, featuring a spiro center and a fluorinated aromatic moiety, makes it an essential building block for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its spirocyclic and fluorophenyl motifs which can enhance blood-brain barrier penetration and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the introduction of fluorine atoms can significantly improve biological activity and environmental persistence.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic frameworks with tailored thermal and optical properties.
• Chemical Biology Probe Development: Serves as a scaffold for creating fluorescent tags, enzyme inhibitors, or other molecular probes used in diagnostic and biochemical research applications.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including asymmetric catalysis, ring-opening reactions, and the construction of complex heterocycles.

Basic Information

Item	Details
Product Name	1-Oxaspiro(4.5)Dec-3-En-2-One, 4-((4-Fluorophenyl)Hydroxymethyl)-3-Methyl-
CAS No.	86560-16-9
Molecular Formula	C₁₇H₁₉FO₃
Molecular Weight	290.33 g/mol
Synonyms	4-[(4-Fluorophenyl)(hydroxy)methyl]-3-methyl-1-oxaspiro[4.5]dec-3-en-2-one; 3-Methyl-4-[(4-fluorophenyl)hydroxymethyl]-1-oxaspiro[4.5]dec-3-en-2-one; 1-Oxaspiro[4.5]dec-3-ene-2-one, 4-[(4-fluorophenyl)hydroxymethyl]-3-methyl-; 86560-16-9; Fluorinated Spirocyclic Enone; 4-(4-Fluorobenzhydryl)-3-methyl-1-oxaspiro[4.5]dec-3-en-2-one
EINECS	Contact for details

Quality Control

Every batch of 1-Oxaspiro(4.5)Dec-3-En-2-One, 4-((4-Fluorophenyl)Hydroxymethyl)-3-Methyl- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.