Description

3-Chloro-1,3,4,5-Tetrahydro-2H-1-Benzazepin-2-One is a high-purity, specialized organic compound serving as a critical building block in advanced chemical synthesis. Its value lies in its unique benzazepinone core, which is a privileged scaffold for developing novel active pharmaceutical ingredients (APIs) and other fine chemicals. This intermediate is essential for research and development laboratories, pharmaceutical companies, and fine chemical manufacturers focused on creating new molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in multi-step synthesis to construct complex heterocyclic compounds due to its reactive chloro and ketone functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize the biological profile of benzazepinone-derived compounds.
• Fine Chemical Production: Serves as a starting material or intermediate in the manufacture of specialty chemicals for agrochemical or material science applications.
• Reference Standard: Used as an analytical standard in quality control laboratories for the identification and quantification of related substances.

Basic Information

Product Name	3-Chloro-1,3,4,5-Tetrahydro-2H-1-Benzazepin-2-One
CAS No.	86499-23-2
Molecular Formula	C10H10ClNO
Molecular Weight	195.65 g/mol
Synonyms	3-Chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one; 3-Chloro-1,2,4,5-tetrahydro-3H-1-benzazepin-2-one; 3-Chloro-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one; 3-Chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-2-one; 86499-23-2; 3-Chloro-1,3,4,5-tetrahydrobenzo[b]azepin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 3-Chloro-1,3,4,5-Tetrahydro-2H-1-Benzazepin-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.