Description

7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of modern fluoroquinolone antibiotics, enabling the development of potent antimicrobial agents. It is primarily required by pharmaceutical manufacturers and R&D organizations focused on active pharmaceutical ingredient (API) production and novel drug discovery.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: A vital precursor in the synthesis of broad-spectrum antibacterial agents such as ciprofloxacin, enrofloxacin, and related derivatives.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design, synthesis, and structure-activity relationship (SAR) studies of new quinolone-based therapeutic candidates.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in large-scale, GMP-compliant production processes for final antibiotic APIs.
• Contract Manufacturing & Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.

Basic Information

Product Name	7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	86483-54-7
Molecular Formula	C15H13ClFNO3
Molecular Weight	309.72 g/mol
Synonyms	Ethyl 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 1-Cyclopropyl-7-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Ciprofloxacin Ethyl Ester; Ciprofloxacin Intermediate; Quinolone Carboxylic Acid Ester; CPFX Ethyl Ester; 86483-54-7
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Manufacturing and quality processes are designed to meet the stringent requirements of pharmaceutical intermediate production. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.