Description

(S)-1-Bromo-4-methyl-2-pentanamine hydrobromide is a high-purity, chiral amine derivative offered as a hydrobromide salt for enhanced stability and handling. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the production of enantiomerically pure pharmaceuticals and specialty chemicals. It is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable access to high-quality, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a chiral amine source or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for metal-catalyzed reactions or as a precursor for organocatalysts.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex natural products, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	(S)-1-Bromo-4-methyl-2-pentanamine hydrobromide
CAS No.	86447-31-6
Molecular Formula	C6H15Br2N
Molecular Weight	269.00 g/mol
Synonyms	(S)-1-Bromo-4-methylpentan-2-amine hydrobromide; (S)-2-Amino-1-bromo-4-methylpentane hydrobromide; (S)-1-Bromo-4-methyl-2-pentylamine HBr; (S)-α-Methyl-γ-bromobutylamine hydrobromide; (S)-1-Bromo-4-methyl-2-aminopentane hydrobromide; L-1-Bromo-4-methyl-2-pentanamine hydrobromide; (S)-1-Bromo-4-methylpentan-2-aminium bromide
EINECS	Contact for details

Quality Control

Every batch of our (S)-1-Bromo-4-methyl-2-pentanamine hydrobromide is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications for identity, purity, and chiral integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters including HPLC/Chiral Purity, Optical Rotation, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Optical Rotation [α]D20	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.