Description

6-Fluoroquinoline-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs), particularly within the quinolone antibiotic and anticancer research fields. Pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers need this high-purity intermediate to create complex molecules with enhanced biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of next-generation fluoroquinolone antibiotics and other bioactive molecules.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the quinoline scaffold imparts specific activity.
• Material Science: Serves as a building block for organic ligands in catalytic systems or for advanced functional materials.
• Chemical Synthesis: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Academic & Industrial R&D: Fundamental research reagent in heterocyclic and fluorine chemistry.

Basic Information

Product Name	6-Fluoroquinoline-2-Carboxylic Acid
CAS No.	86324-51-8
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	2-Quinolinecarboxylic acid, 6-fluoro-; 6-Fluoro-2-quinolinecarboxylic acid; 6-Fluoroquinoline-2-carboxylic acid; 6-Fluoro-2-carboxyquinoline; 6-Fluoroquinaldic acid; 86324-51-8; 6-Fluoroquinoline-2-carboxylate; 6-Fluoro-2-quinoline carboxylate
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.