Description

6-Fluoroquinoline-2-Carbonitrile is a high-value, multi-functional heterocyclic building block and key synthetic intermediate. Its core value proposition lies in its unique molecular structure, which combines a fluorinated quinoline scaffold with a reactive nitrile group, enabling precise modifications for advanced material and pharmaceutical development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antimicrobial agents, and other biologically active quinoline derivatives.
• Agrochemical Research: Serves as a key building block for creating new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials, due to its electron-deficient quinoline core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The fluorinated quinoline structure makes it a suitable starting point for synthesizing fluorescent dyes and molecular probes for bioimaging and sensing applications.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	6-Fluoroquinoline-2-Carbonitrile
CAS No.	86324-50-7
Molecular Formula	C10H5FN2
Molecular Weight	172.16 g/mol
Synonyms	2-Cyano-6-fluoroquinoline; 6-Fluoro-2-quinolinecarbonitrile; 6-Fluoroquinoline-2-carbonitrile; 6-Fluoro-2-cyanoquinoline; Quinoline-2-carbonitrile, 6-fluoro-; 86324-50-7; 6-Fluoro-2-quinolyl cyanide
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline-2-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.