Description

3,3',5,5'-Tetrafluorodiethylstilbestrol Quinone is a specialized fluorinated derivative of diethylstilbestrol, a synthetic non-steroidal estrogen. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key synthetic intermediate or a potential active pharmaceutical ingredient (API) precursor. Its precise fluorination pattern makes it valuable for researchers in medicinal chemistry, pharmacology, and organic synthesis targeting hormone-related pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel fluorinated steroid analogs and hormone receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents with enhanced metabolic stability and binding affinity.
• Biochemical Probe: Acts as a tool compound for investigating estrogen receptor interactions and signaling mechanisms in biological systems.
• Organic Synthesis: Employed in advanced organic transformations to create complex, fluorinated molecular architectures for various research applications.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	3,3',5,5'-Tetrafluorodiethylstilbestrol Quinone
CAS No.	86321-57-5
Molecular Formula	C20H16F4O2
Molecular Weight	364.34 g/mol
Synonyms	3,3',5,5'-Tetrafluoro-4,4'-(1,2-diethyl-1,2-ethenediyl)bis[phenol] quinone; Tetrafluoro-DES Quinone; 4,4'-(1,2-Diethyl-1,2-ethenediyl)bis(2,6-difluorophenol) quinone; DES-Tetrafluoro Quinone; Fluorinated Diethylstilbestrol Quinone; NSC 112931 (related); Stilbestrol Tetrafluoro Quinone Derivative
EINECS	Contact for details

Quality Control

Our 3,3',5,5'-Tetrafluorodiethylstilbestrol Quinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.