Description

1-(4-Bromo-Phenyl)-3-Azabicyclo[3.1.0]Hexane is a high-purity, advanced pharmaceutical intermediate featuring a unique azabicyclo[3.1.0]hexane scaffold. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained, three-dimensional bicyclic structure.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for potential APIs.
• Ligand and Catalyst Synthesis: Potential precursor for creating specialized ligands or organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in exploratory research for developing new chemical entities with therapeutic potential.

Basic Information

Product Name	1-(4-Bromo-Phenyl)-3-Azabicyclo[3.1.0]Hexane
CAS No.	86215-40-9
Molecular Formula	C11H12BrN
Molecular Weight	238.13 g/mol
Synonyms	3-(4-Bromophenyl)-3-azabicyclo[3.1.0]hexane; 1-(4-Bromophenyl)-3-azabicyclo[3.1.0]hexane; 4-Bromo-N-(bicyclo[3.1.0]hex-3-yl)aniline; 3-Azabicyclo[3.1.0]hexane, 1-(4-bromophenyl)-; 1-(p-Bromophenyl)-3-azabicyclo[3.1.0]hexane
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-Phenyl)-3-Azabicyclo[3.1.0]Hexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.