Description

(R)-α-Benzyl-L-Proline-Hcl CAS NO 86116-84-9 is a high-purity chiral proline derivative, a critical building block in asymmetric synthesis and pharmaceutical development. Its value lies in its role as a key intermediate for creating enantiomerically pure compounds, particularly in the synthesis of complex active pharmaceutical ingredients (APIs). This product is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of high-quality chiral auxiliaries and intermediates.

Application

• As a chiral auxiliary or ligand in asymmetric catalytic reactions.
• Key intermediate in the synthesis of pharmaceutical APIs, particularly for cardiovascular and central nervous system (CNS) drugs.
• Building block for peptidomimetics and novel drug candidates in medicinal chemistry research.
• Precursor for the development of organocatalysts used in green chemistry applications.
• Starting material for the synthesis of specialized amino acid derivatives and custom peptides.
• Used in agrochemical research for creating enantiomerically pure active ingredients.

Basic Information

Product Name	(R)-α-Benzyl-L-Proline Hydrochloride
CAS No.	86116-84-9
Molecular Formula	C₁₃H₁₇NO₂·HCl
Molecular Weight	255.74 g/mol
Synonyms	(R)-α-Benzyl-L-proline hydrochloride; (R)-1-Benzyl-L-proline hydrochloride; (R)-N-Benzyl-L-proline hydrochloride; (R)-N-Benzylproline hydrochloride; (2R)-1-Benzylpyrrolidine-2-carboxylic acid hydrochloride; (R)-N-Benzylproline HCl; (R)-Benzylproline HCl; (R)-α-Benzylproline hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-α-Benzyl-L-Proline-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.