Description

(1R-(1A,2B,3A))-(+)-3-Me-2-(Nitromethyl)-5-Oxocyclopentaneacetic Acid, 98 is a high-purity, chiral cyclopentane derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for the development of novel pharmaceuticals and fine chemicals, offering precise stereochemistry and functional group diversity. It is primarily needed by research and development chemists in the pharmaceutical industry for the synthesis of complex, biologically active molecules, including potential antiviral and anti-inflammatory agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for antiviral and anti-inflammatory drug candidates.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to construct complex molecular architectures with defined three-dimensional configurations.
• Prostaglandin Analog Synthesis: Serves as a precursor in the synthetic pathways for prostaglandin and prostacyclin analogs, which are important bioactive lipids.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore new chemical entities.
• Fine Chemical Production: Used in the manufacture of specialty chemicals and advanced materials that require high stereochemical purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis within university and corporate research laboratories.

Basic Information

Item	Detail
Product Name	(1R-(1A,2B,3A))-(+)-3-Me-2-(Nitromethyl)-5-Oxocyclopentaneacetic Acid, 98
CAS No.	86023-17-8
Molecular Formula	C10H15NO5
Molecular Weight	229.23 g/mol
Synonyms	(1R,2S,3R)-3-Methyl-2-(nitromethyl)-5-oxocyclopentaneacetic Acid; (+)-3-Methyl-2-(nitromethyl)-5-oxocyclopentaneacetic Acid; (1R-(1-alpha,2-beta,3-alpha))-3-Methyl-2-(nitromethyl)-5-oxocyclopentaneacetic Acid; NSC 339586; 3-Methyl-2-nitromethyl-5-oxocyclopentaneacetic Acid; Cyclopentaneacetic acid, 3-methyl-2-(nitromethyl)-5-oxo-, (1R,2S,3R)-
EINECS	Contact for details

Quality Control

Our (1R-(1A,2B,3A))-(+)-3-Me-2-(Nitromethyl)-5-Oxocyclopentaneacetic Acid, 98 is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC and chiral analysis, to ensure identity, purity, and stereochemical integrity meet the specified standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.