Description

α-(4-Bromophenyl)Pyridine-2-Acetonitrile is a versatile brominated heterocyclic building block, a key intermediate in advanced organic synthesis. Its molecular structure, featuring both a pyridine ring and a reactive nitrile group, makes it invaluable for constructing complex pharmacophores and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic system.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive materials due to its conjugated system.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags to study biological processes.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis houses serving diverse R&D and scale-up projects.

Basic Information

Product Name	α-(4-Bromophenyl)Pyridine-2-Acetonitrile
CAS No.	85750-24-9
Molecular Formula	C₁₃H₉BrN₂
Molecular Weight	273.13 g/mol
Synonyms	2-[(4-Bromophenyl)(pyridin-2-yl)methyl]acetonitrile; (4-Bromophenyl)(pyridin-2-yl)acetonitrile; 2-(4-Bromobenzyl)-2-pyridylacetonitrile; α-(4-Bromophenyl)-2-pyridineacetonitrile; 4-Bromo-α-(2-pyridyl)benzeneacetonitrile; 85750-24-9; (4-Bromophenyl)(2-pyridinyl)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of α-(4-Bromophenyl)Pyridine-2-Acetonitrile is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, GC, NMR, and mass spectrometry is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.