Description

4-(1,1,2,2-Tetrafluoroethoxy)Phenol is a specialized fluorinated phenolic compound, serving as a critical building block for advanced material synthesis. Its unique structure, featuring a tetrafluoroethoxy substituent, provides enhanced chemical stability and specific electronic properties sought after in high-performance applications. This intermediate is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and pesticides where the fluorinated group can enhance target binding and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs) to modify charge transport and emission properties.
• Specialty Polymer Modifier: Incorporation into polymer backbones to impart specific characteristics such as chemical resistance, low surface energy, or altered thermal properties.
• Advanced Material Research: Valuable reagent in academic and industrial R&D for exploring new fluorinated compounds with potential applications in coatings, electronics, and nanotechnology.

Basic Information

Product Name	4-(1,1,2,2-Tetrafluoroethoxy)Phenol
CAS No.	85578-29-6
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	p-(1,1,2,2-Tetrafluoroethoxy)phenol; 4-(Perfluoroethoxy)phenol; Phenol, 4-(1,1,2,2-tetrafluoroethoxy)-; 1-(1,1,2,2-Tetrafluoroethoxy)-4-hydroxybenzene; 4-Hydroxy-α,α,β,β-tetrafluorophenetole; HQ-TFE; Tetrafluoroethoxyphenol
EINECS	Contact for details

Quality Control

Our production of 4-(1,1,2,2-Tetrafluoroethoxy)Phenol adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, with specifications tailored to meet the rigorous demands of fine chemical and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.