Description

3-Methylnitrosaminopropionaldehyde is a specialized nitrosamine compound of significant interest in advanced chemical research and development. Its primary value lies as a critical reference standard and synthetic intermediate for analytical and investigative purposes. This product is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and toxicology sectors, where precise chemical standards are required for method development, validation, and impurity profiling.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and the quantification of nitrosamine impurities in pharmaceutical APIs and finished drug products.
• Pharmaceutical Research: Serves as a key intermediate or impurity marker in the study of nitrosamine formation pathways and the development of mitigation strategies during drug synthesis.
• Toxicological Studies: Employed in laboratory research to investigate the metabolic pathways, genotoxicity, and carcinogenic potential of N-nitroso compounds.
• Method Development: Critical for developing and validating highly sensitive analytical methods, such as LC-MS/MS and GC-MS, for trace-level detection of nitrosamines in complex matrices.
• Regulatory Compliance Testing: Supports testing protocols to ensure compliance with stringent global regulatory guidelines (e.g., FDA, EMA) regarding nitrosamine impurities in pharmaceuticals.
• Chemical Synthesis: Acts as a building block or precursor in organic synthesis for research-scale preparation of more complex molecules containing nitrosamine functionalities.

Basic Information

Product Name	3-Methylnitrosaminopropionaldehyde
CAS No.	85502-23-4
Molecular Formula	C4H8N2O2
Molecular Weight	116.12 g/mol
Synonyms	3-Methyl-N-nitrosaminopropionaldehyde; N-Nitroso-N-methyl-3-aminopropionaldehyde; MNPA; β-(N-Methyl-N-nitrosamino)propionaldehyde; N-Methyl-N-nitroso-β-alaninal; Propionaldehyde, 3-(methylnitrosoamino)-
EINECS	Contact for details

Quality Control

Every batch of 3-Methylnitrosaminopropionaldehyde is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for reference materials. Comprehensive Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is between -20°C to -10°C to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Yellow to orange liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.