Description

3-(4-Bromophenyl)-2-Chloroquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a quinoline core with halogenated phenyl substituents, enabling precise molecular modifications. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinoline scaffold.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other electronic materials where specific luminescent or charge-transport properties are required.
• Chemical Synthesis: Acts as a versatile intermediate for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) facilitated by the bromine and chlorine handles.
• Ligand and Catalyst Development: Utilized in the design of novel chelating ligands for metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	3-(4-Bromophenyl)-2-Chloroquinoline
CAS No.	85274-82-4
Molecular Formula	C15H9BrClN
Molecular Weight	318.60 g/mol
Synonyms	2-Chloro-3-(4-bromophenyl)quinoline; 3-(p-Bromophenyl)-2-chloroquinoline; 2-Chloro-3-(4'-bromophenyl)quinoline; Quinoline, 2-chloro-3-(4-bromophenyl)-; 85274-82-4; 3-(4-Bromophenyl)-2-chloro-quinoline
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Bromophenyl)-2-Chloroquinoline is manufactured and tested under strict quality management protocols to ensure it meets the high standards required for research and development. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.