Description

2-Chloro-6-Methoxy-3-Phenylquinoline is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Research: Used as a core scaffold for developing new pesticides, herbicides, and fungicides due to the bioactive quinoline structure.
• Material Science & OLED Development: Acts as a building block for creating organic light-emitting diode (OLED) materials and other functional organic electronic components.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry applications.
• Chemical Research & Development: Serves as a standard or reference compound in analytical method development and structure-activity relationship (SAR) studies.
• Academic Research: Used in universities and research institutes for exploring new organic reactions and synthesizing complex heterocyclic systems.

Basic Information

Product Name	2-Chloro-6-Methoxy-3-Phenylquinoline
CAS No.	85274-57-3
Molecular Formula	C₁₆H₁₂ClNO
Molecular Weight	269.73 g/mol
Synonyms	3-Phenyl-2-chloro-6-methoxyquinoline; 2-Chloro-6-methoxy-3-phenylquinoline; Quinoline, 2-chloro-6-methoxy-3-phenyl-; 6-Methoxy-2-chloro-3-phenylquinoline; 2-Chloro-3-phenyl-6-methoxyquinoline; 85274-57-3; 3-Phenyl-6-methoxy-2-chloroquinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methoxy-3-Phenylquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.