Description

Methyl 2,2,4-Trichloro-3-Oxobutyrate is a specialized chlorinated ketoester building block of significant importance in advanced organic synthesis. Its reactive carbonyl and ester functionalities, flanked by chlorine atoms, make it a versatile precursor for constructing complex molecular architectures. This high-value intermediate is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring chlorinated or heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for creating novel bioactive compounds.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, dyes, and performance materials where specific chlorinated structures are required.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for exploring new reaction pathways, such as cyclization and condensation reactions, due to its multiple reactive centers.
• Chemical Intermediate for Complex Esters: Utilized in the synthesis of more complex ester derivatives with potential applications in polymer chemistry and material science.

Basic Information

Product Name	Methyl 2,2,4-Trichloro-3-Oxobutyrate
CAS No.	85153-68-0
Molecular Formula	C5H5Cl3O3
Molecular Weight	219.45 g/mol
Synonyms	Methyl 2,2,4-trichloroacetoacetate; 2,2,4-Trichloro-3-oxobutanoic acid methyl ester; Methyl 2,2,4-trichloro-3-oxobutanoate; Acetoacetic acid, 2,2,4-trichloro-, methyl ester; Methyl trichloroacetoacetate; 3-Oxobutyric acid, 2,2,4-trichloro-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,2,4-Trichloro-3-Oxobutyrate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The product is compatible with strong acid/organic solvent environments but should be handled with appropriate chemical safety precautions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density	~1.5 g/cm³ (at 20°C)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.