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Ethanol, 2-[2-[2-(2-Bromoethoxy)Ethoxy]Ethoxy]- CAS NO 85141-94-2


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CAS No.:85141-94-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethanol, 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]- is a specialized bromo-terminated polyethylene glycol (PEG) derivative, serving as a crucial bifunctional linker and building block in advanced organic synthesis. Its core value lies in its ability to introduce reactive bromoalkyl groups and hydrophilic PEG spacers into target molecules, facilitating the creation of functionalized materials and bioconjugates. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and materials science industries who require precise molecular modification and controlled functionalization.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing prodrugs, drug-polymer conjugates, and targeted therapeutic agents.
  • Bioconjugation & PEGylation: Used to attach polyethylene glycol (PEG) chains to peptides, proteins, or antibodies to improve solubility, stability, and circulation time.
  • Polymer & Materials Science: Serves as a functional initiator or cross-linking agent in the synthesis of smart polymers, hydrogels, and surface coatings.
  • Chemical Linker: Acts as a versatile spacer arm in the development of diagnostic reagents, biosensors, and affinity chromatography media.
  • Surface Functionalization: Employed to modify nanoparticles, quantum dots, and other nanomaterials with reactive bromo groups for further derivatization.
  • Organic Synthesis: A valuable reagent for introducing polyether chains and halogen functionality in complex molecule construction.

Basic Information

Product Name Ethanol, 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-
CAS No. 85141-94-2
Molecular Formula C10H21BrO4
Molecular Weight 285.18 g/mol
Synonyms 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]ethanol; 2-Bromoethyl-triethylene glycol; Br-PEG3-OH; 3,6,9-Trioxa-12-bromododecan-1-ol; Triethylene glycol monobromoethyl ether; Bromo-PEG3-alcohol; 11-Bromo-3,6,9-trioxaundecan-1-ol; 2-(2-(2-(2-Bromoethoxy)ethoxy)ethoxy)ethanol
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Quality Control

Our Ethanol, 2-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including NMR (¹H and ¹³C), HPLC for purity assessment, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is supplied with each batch, confirming compliance with specified parameters. Custom synthesis and purification to meet specific research or cGMP-grade requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its moisture-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 0.5%
Refractive Index 1.460 - 1.470
Density ~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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