Description

(9S)-9-Hydroxy-6'-Methoxycinchonanium Nitrite is a high-purity, specialized cinchona alkaloid derivative. This compound is valued for its role as a chiral intermediate and catalyst in advanced asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to control stereochemistry in complex molecular architectures.

Application

• Asymmetric Synthesis Catalyst: Employed as a chiral phase-transfer catalyst or organocatalyst for enantioselective alkylation, Michael addition, and other C-C bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemical configurations.
• Chiral Resolution Agent: Used in the separation and purification of enantiomers through diastereomeric salt formation or chiral chromatography.
• Research & Development: A critical reagent for method development and exploratory chemistry in academic and industrial R&D settings focused on stereochemistry.
• Fine Chemical Production: Utilized in the manufacture of high-value, optically active compounds for agrochemicals, flavors, and fragrances.

Basic Information

Product Name	(9S)-9-Hydroxy-6'-Methoxycinchonanium Nitrite
CAS No.	85135-83-7
Molecular Formula	C₂₁H₂₇N₃O₄
Molecular Weight	385.46 g/mol
Synonyms	9-Hydroxy-6'-methoxycinchonanium nitrite; (9S)-Cinchonan-9-ol, 6'-methoxy-, nitrate (salt); 6'-Methoxycinchonidine nitrite; Cinchonanium, 9-hydroxy-6'-methoxy-, nitrate; (8α,9R)-6'-Methoxycinchonan-9-ol nitrate; Nitrous acid, (9S)-9-hydroxy-6'-methoxycinchonanium; Cinchonidine derivative nitrate salt
EINECS	Contact for details

Quality Control

Our (9S)-9-Hydroxy-6'-Methoxycinchonanium Nitrite is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for use in sensitive asymmetric synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and a strong oxidizer; keep the container tightly sealed and store separately from combustible materials and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.